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eISSN: 2083-8441
ISSN: 2081-237X
Pediatric Endocrinology Diabetes and Metabolism
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SCImago Journal & Country Rank
3/2023
vol. 29
 
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abstract:
Case report

Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review

Patrycja Dasiewicz
1
,
Elżbieta Moszczyńska
1
,
Danuta Perek
2
,
Dariusz Polnik
3
,
Maria Stepaniuk
4
,
Joanna Trubicka
4
,
Wiesława Grajkowska
4

  1. Department of Endocrinology, Children's Memorial Health Institute, Warsaw, Poland
  2. Department of Oncology, Children's Memorial Health Institute, Warsaw, Poland
  3. Department of Surgery, Children's Memorial Health Institute, Warsaw, Poland
  4. Department of Pathology, Children's Memorial Health Institute, Warsaw, Poland
Pediatr Endocrinol Diabetes Metab 2023; 29 (3): 202-208
Online publish date: 2023/10/23
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Background
Adrenocortical carcinoma (ACC) accounts for 0.2% of childhood malignancies. The most common symptom in children is rapidly progressive androgenization. Herein, we report a case of a patient with symptoms of hypercortisolaemia and androgenization, who was diagnosed with ACC.

Case presentation
In a 10-year-old patient with ACC the course of the disease was complicated by 3 recurrences. She was treated with surgery, chemo-, and radiotherapy. Currently, 8 years after the end of treatment, there have been no signs of recurrence.

Conclusions
A patient after ACC treatment requires regular check-ups and long-term observation. Constant supervision enables early diagnosis of disease recurrence, and the use of treatment improves the prognosis.

keywords:

adrenocortical carcinoma, adrenocortical tumour, mitotan


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